A0A317CPJ1

Inosine-5'-monophosphate dehydrogenase

UniProtKB/TrEMBL protein
Short nameA0A317CPJ1_9GAMM
Length486 amino acids
SpeciesLeucothrix pacifica
ProteomeUP000245539
GeneguaB
Function
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growt...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
148650100150200250300350400450
200400
IMPDH
Active site
CBS_pair_IMPDH
Ligand binding site I
Ligand binding site II
IMPDH
BINDING: IMP.
REGION: IMP binding.
METAL: Potassium; via carbonyl oxygen.
NP_BIND: NAD.
ACT_SITE: Proton acceptor.
ACT_SITE: Thioimidate intermediate.
PIRSR
NP_BIND: FMN.
BINDING: Glyoxylate.
BINDING: FMN.
ACT_SITE: Thioimidate intermediate.
METAL: Potassium; via carbonyl oxygen.

InterPro GO terms

Panther GO terms
PTHR11911:SF111
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