A0A3N6PZJ2
Inosine-5'-monophosphate dehydrogenase
UniProtKB/TrEMBL protein
Short name | A0A3N6PZJ2_9BURK |
Length | 486 amino acids |
Species | Paraburkholderia dinghuensis |
Proteome | UP000272778 |
Gene | guaB |
Function | Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growt... |
Family membership |
Entry matches to this protein
Representative families
Representative domains
Active site
Ligand binding site I
Ligand binding site II
METAL: Potassium; via carbonyl oxygen.
BINDING: IMP.
REGION: IMP binding.
ACT_SITE: Thioimidate intermediate.
ACT_SITE: Proton acceptor.
NP_BIND: NAD.
PIRSR
NP_BIND: FMN.
BINDING: Glyoxylate.
ACT_SITE: Thioimidate intermediate.
METAL: Potassium; via carbonyl oxygen.
InterPro GO terms
biological process
molecular function
cellular component
- None
Panther GO terms
PTHR11911:SF111
biological process
molecular function
cellular component