A0A485MCG1

E3 ubiquitin-protein ligase RNF8

UniProtKB/TrEMBL protein
Short nameA0A485MCG1_LYNPA
Length497 amino acids
SpeciesLynx pardinus (Iberian lynx)
ProteomeUP000386466
GeneRNF8
Function
E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSB...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
149750100150200250300350400450
200400
RING-HC_RNF8
E2 binding site
Homodimer interface
FHA_RNF8
Phosphopeptide binding site

InterPro GO terms

Panther GO terms
PTHR15067:SF4
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.