A0A5C8W7I3

Phosphoglycolate phosphatase

UniProtKB/TrEMBL protein
Short nameA0A5C8W7I3_9HYPH
Length227 amino acids
SpeciesMethylobacterium sp. WL6
Genegph
Function
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative s...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
122720406080100120140160180200220
100200
C1.5.6:_HAD__Beta-PGM__Phospha
Mg2+ ligand, nucleophile: attacks phosphate moiety of intermediate to form covalent intermediate
PIRSR
BINDING: substrate
BINDING: Mg(2+)
METAL: Magnesium.
ACT_SITE: Nucleophile.
ACT_SITE: Proton donor.
BINDING: Substrate.
REGION: Substrate binding.
METAL: Magnesium 1.
METAL: Magnesium 2.
METAL: Magnesium 2; via carbonyl oxygen.
SITE: Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups.

InterPro GO terms

Panther GO terms
PTHR43434:SF1
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