A0A727BED0

Siroheme synthase

UniProtKB/TrEMBL protein
Short nameA0A727BED0_SALET
Length457 amino acids
SpeciesSalmonella enterica subsp. enterica serovar Ank
GenecobA
Function
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlori...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
145750100150200250300350400450
200400
SUMT
Homodimer interface
Active site
SAM binding site
Chemical substrate binding site
Sirohaem_synth
ACT_SITE: Proton donor.
ACT_SITE: Proton acceptor.
PIRSR
BINDING: S-adenosyl-L-methionine; via carbonyl oxygen.
REGION: S-adenosyl-L-methionine binding.
BINDING: S-adenosyl-L-methionine; via amide nitrogen and carbonyl oxygen.

InterPro GO terms

Panther GO terms
PTHR45790:SF1
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