A0A8D2F0I4
Double-strand break repair protein
UniProtKB/TrEMBL protein
Short name | A0A8D2F0I4_THEGE |
Length | 708 amino acids |
Species | Theropithecus gelada (Gelada baboon) |
Proteome | UP000694411 |
Gene | MRE11 |
Function | Core component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homo... |
Family membership |
Entry matches to this protein
Representative families
Representative domains
MobiDB-lite: Consensus Disorder Prediction
Polar
Positive Polyelectrolyte
Negative Polyelectrolyte
Low complexity
DNA binding site
Heterodimer interface
Homodimer interface
Metal binding site
Active site
ACT_SITE: Proton donor.
coils: Coil
InterPro GO terms
biological process
molecular function
cellular component
Panther GO terms
PTHR10139:SF1
biological process
- telomere maintenance (GO:0000723)
- double-strand break repair via homologous recombination (GO:0000724)
- double-strand break repair via nonhomologous end joining (GO:0006303)
- mitotic G2 DNA damage checkpoint signaling (GO:0007095)
- mitotic intra-S DNA damage checkpoint signaling (GO:0031573)
- meiotic DNA double-strand break formation (GO:0042138)
- mitochondrial double-strand break repair via homologous recombination (GO:0097552)
molecular function
cellular component