A0A8E6U6I7
Fatty acid oxidation complex subunit alpha
UniProtKB/TrEMBL protein
Short name | A0A8E6U6I7_SALER |
Length | 729 amino acids |
Species | Salmonella enterica |
Gene | fadB |
Function | Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrat... |
Family membership |
Entry matches to this protein
Representative families
Representative domains
Trimer interface
Substrate binding site
Oxyanion hole (OAH) forming residues
PIRSR
SITE: Important for catalytic activity.
NP_BIND: NAD.
BINDING: NAD.
ACT_SITE: For hydroxyacyl-coenzyme A dehydrogenase activity.
SITE: Important for long-chain enoyl-CoA hydratase activity.
SITE: Important for hydroxyacyl-coenzyme A dehydrogenase activity.
InterPro GO terms
biological process
molecular function
- NAD+ binding (GO:0070403)
- oxidoreductase activity (GO:0016491)
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
- 3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857)
- delta(3)-delta(2)-enoyl-CoA isomerase activity (GO:0004165)
- enoyl-CoA hydratase activity (GO:0004300)
- 3-hydroxybutyryl-CoA epimerase activity (GO:0008692)
- catalytic activity (GO:0003824)
cellular component
Panther GO terms
PTHR43612:SF3
biological process
molecular function
cellular component