A0A8I3WB02
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
UniProtKB/TrEMBL protein
Short name | A0A8I3WB02_CALJA |
Length | 1315 amino acids |
Species | Callithrix jacchus (White-tufted-ear marmoset) |
Proteome | UP000008225 |
Gene | PLCG1 |
Function | Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative families
Representative domains
Ca2+ binding pocket
Putative Ca binding site
Catalytic site
Phosphotyrosine binding pocket
Hydrophobic binding pocket
Hydrophobic binding pocket
Phosphotyrosine binding pocket
Peptide ligand binding site
Rac2 binding site
Putative Rac1 binding site
Putative phosphoinositide binding site
MOD_RES: Phosphoserine.
PIRSR
BINDING: Ca(2+)
ACT_SITE:
BINDING: Ca(2+)
BINDING: Substrate.
METAL: Calcium 1; catalytic.
METAL: Calcium 2; via carbonyl oxygen.
METAL: Calcium 3.
InterPro GO terms
biological process
molecular function
cellular component
- None
Panther GO terms
PTHR10336:SF173
biological process
molecular function
cellular component