B1H1F5
Interleukin-1 receptor-associated kinase 4
UniProtKB/TrEMBL protein
Short name | B1H1F5_XENTR |
Length | 457 amino acids |
Species | Xenopus tropicalis (Western clawed frog) |
Proteome | UP000008143 |
Gene | irak4 |
Function | Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative families
Representative domains
IRAK4-MyD88 interaction site
IRAK4-IRAK2 interaction site
Activation loop (A-loop)
Polypeptide substrate binding site
ATP binding site
Active site
ACT_SITE: Proton acceptor.
BINDING: ATP.
NP_BIND: ATP.
PIRSR
BINDING: ATP
ACT_SITE: Proton acceptor.
NP_BIND: ATP.
BINDING: ATP.
BINDING: ATP
METAL: Magnesium; via carbonyl oxygen.
METAL: Magnesium.
CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
coils: Coil
InterPro GO terms
biological process
molecular function
cellular component
- None