B1H1F5

Interleukin-1 receptor-associated kinase 4

UniProtKB/TrEMBL protein
Short nameB1H1F5_XENTR
Length457 amino acids
SpeciesXenopus tropicalis (Western clawed frog)
ProteomeUP000008143
Geneirak4
Function
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
145750100150200250300350400450
200400
Death_IRAK4
IRAK4-MyD88 interaction site
IRAK4-IRAK2 interaction site
STKc_IRAK4
Activation loop (A-loop)
Polypeptide substrate binding site
ATP binding site
Active site
IRAK4IRAK4
ACT_SITE: Proton acceptor.
BINDING: ATP.
NP_BIND: ATP.
PIRSR
BINDING: ATP
ACT_SITE: Proton acceptor.
NP_BIND: ATP.
BINDING: ATP.
BINDING: ATP
METAL: Magnesium; via carbonyl oxygen.
METAL: Magnesium.
CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)

InterPro GO terms

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