C3YPU5

Inosine-5'-monophosphate dehydrogenase

UniProtKB/TrEMBL protein
Short nameC3YPU5_BRAFL
Length556 amino acids
SpeciesBranchiostoma floridae (Florida lancelet)
GeneBRAFLDRAFT_121137
Function
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growt...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
155650100150200250300350400450500550
200400
IMPDH
Active site
CBS_pair_IMPDH
Ligand binding site I
Ligand binding site II
PIRSR
ACT_SITE: Proton acceptor.
NP_BIND: NAD.
ACT_SITE: Thioimidate intermediate.
METAL: Potassium; via carbonyl oxygen.

InterPro GO terms

Panther GO terms
PTHR11911:SF111
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