G1DFN8
DNA repair nuclease/redox regulator APEX1
UniProtKB/TrEMBL protein
Short name | G1DFN8_CAPHI |
Length | 318 amino acids |
Species | Capra hircus (Goat) |
Gene | APEX1 |
Function | Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative families
Representative domains
DNA binding site
Metal binding site A
Putative phosphate binding site
Metal binding site B
Active site
AP binding site
Putative catalytic site
PIRSR
ACT_SITE: Proton donor/acceptor
ACT_SITE:
ACT_SITE: Proton acceptor
BINDING: Mg(2+)
SITE: Interaction with DNA substrate
SITE: Important for catalytic activity
SITE: Transition state stabilizer
InterPro GO terms
biological process
molecular function
cellular component
- None