O08538
Angiopoietin-1
UniProtKB/Swiss-Prot protein
Short name | ANGP1_MOUSE |
Length | 498 amino acids |
Species | Mus musculus (Mouse) |
Proteome | UP000000589 |
Gene | Angpt1 |
Function | Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganizati... |
Family membership |
Entry matches to this protein
Representative domains
coils: Coil
phobius: SIGNAL_PEPTIDE_N_REGION
phobius: SIGNAL_PEPTIDE
phobius: SIGNAL_PEPTIDE_H_REGION
phobius: SIGNAL_PEPTIDE_C_REGION
phobius: NON_CYTOPLASMIC_DOMAIN
signalp e: SignalP-noTM
InterPro GO terms
Panther GO terms
PTHR47221:SF6
biological process
molecular function
cellular component