P55073
Thyroxine 5-deiodinase
UniProtKB/Swiss-Prot protein
Short name | IOD3_HUMAN |
Length | 304 amino acids |
Species | Homo sapiens (Human) |
Proteome | UP000005640 |
Gene | DIO3 |
Function | Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature... |
Family membership |
Entry matches to this protein
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Summary
Full
Representative families
phobius: NON_CYTOPLASMIC_DOMAIN
phobius: TRANSMEMBRANE
phobius: CYTOPLASMIC_DOMAIN
tmhmm: TMhelix
InterPro GO terms
biological process
- None
molecular function
cellular component
- None
Panther GO terms
PTHR11781:SF4
biological process
molecular function
cellular component
- None