P9WKK6
Isocitrate lyase 1
UniProtKB/Swiss-Prot protein
Short name | ACEA1_MYCTO |
Length | 428 amino acids |
Species | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
Proteome | UP000001020 |
Gene | icl1 |
Function | Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic... |
Family membership |
Entry matches to this protein
Representative families
Representative domains
Oligomerization interface
Active site
Metal binding site
METAL: Magnesium.
ACT_SITE: Proton acceptor.
InterPro GO terms
biological process
molecular function
cellular component
- None
Panther GO terms
PTHR21631:SF3
biological process
- None
molecular function
cellular component