Q08351
Thrombopoietin receptor
UniProtKB/Swiss-Prot protein
Short name | TPOR_MOUSE |
Length | 625 amino acids |
Species | Mus musculus (Mouse) |
Proteome | UP000000589 |
Gene | Mpl |
Function | Receptor for thrombopoietin that regulates hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation (PubMed:8630375, PubMed:9122198, PubMed:9639492). Upon activation by THPO, induces rapid tyrosine phosphorylation and ac... |
Family membership | None predicted |
Isoforms |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative domains
phobius: SIGNAL_PEPTIDE_N_REGION
phobius: SIGNAL_PEPTIDE
phobius: SIGNAL_PEPTIDE_H_REGION
phobius: SIGNAL_PEPTIDE_C_REGION
phobius: NON_CYTOPLASMIC_DOMAIN
phobius: TRANSMEMBRANE
phobius: CYTOPLASMIC_DOMAIN
signalp e: SignalP-noTM
signalp g+: SignalP-TM
tmhmm: TMhelix
InterPro GO terms
biological process
- None
molecular function
cellular component
Panther GO terms
PTHR23037:SF28
biological process
molecular function
cellular component