Q09XV5

Chromodomain-helicase-DNA-binding protein 8

UniProtKB/Swiss-Prot protein
Short nameCHD8_MOUSE
Length2582 amino acids
SpeciesMus musculus (Mouse)
ProteomeUP000000589
GeneChd8
Function
DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting h...
Family membership
Isoforms
Entry matches to this protein
125822004006008001,0001,2001,4001,6001,8002,0002,2002,400
10002000
HE…SNF2-rel_…
Representative domains
MobiDB-lite: Consensus Disorder Prediction
Polar
Low complexity
Proline-rich
Polyampholyte
Positive Polyelectrolyte
Negative Polyelectrolyte
Putative peptide binding site
Peptide binding site
S…
ATP binding site
DNA binding site

InterPro GO terms

cellular component

  • None
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