Q1M003
Protein Nef
UniProtKB/TrEMBL protein
Short name | Q1M003_HV1 |
Length | 209 amino acids |
Species | Human immunodeficiency virus type 1 (HIV-1) |
Gene | nef |
Function | Bypasses host T-cell signaling by inducing a transcriptional program nearly identical to that of anti-CD3 cell activation. Interaction with TCR-zeta chain up-regulates the Fas ligand (FasL). Increasing surface FasL molecules and decreasing surface MH... |
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