Q7Z527
GMP reductase
UniProtKB/TrEMBL protein
Short name | Q7Z527_HUMAN |
Length | 350 amino acids |
Species | Homo sapiens (Human) |
Gene | GMPR |
Function | Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides |
Family membership |
Entry matches to this protein
Representative families
Representative domains
Active site
METAL: Potassium; via carbonyl oxygen.
ACT_SITE: Thioimidate intermediate.
PIRSR
NP_BIND: NAD.
METAL: Potassium; via carbonyl oxygen.
InterPro GO terms
biological process
molecular function
cellular component