Q8YP80
Formamidopyrimidine-DNA glycosylase
UniProtKB/Swiss-Prot protein
Short name | FPG_NOSS1 |
Length | 283 amino acids |
Species | Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) |
Proteome | UP000002483 |
Gene | mutM |
Function | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as a DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurin... |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative families
Representative domains
H2TH interface
Putative reading head residues
DNA binding site
Putative catalytic residues
Turnover-facilitating residue
8OG recognition residue
Intercalation triad
Catalytic residue
InterPro GO terms
biological process
molecular function
- DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0003906)
- zinc ion binding (GO:0008270)
- DNA N-glycosylase activity (GO:0019104)
- damaged DNA binding (GO:0003684)
- hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799)
- oxidized purine nucleobase lesion DNA N-glycosylase activity (GO:0008534)
- nucleic acid binding (GO:0003676)
- DNA binding (GO:0003677)
cellular component
- None