Q9I8N6

Macrophage colony-stimulating factor 1 receptor

UniProtKB/Swiss-Prot protein
Short nameCSF1R_DANRE
Length977 amino acids
SpeciesDanio rerio (Zebrafish)
ProteomeUP000000437
Genecsf1r
Function
Tyrosine-protein kinase that acts as a cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophage...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
1977100200300400500600700800900
500
PTKc_CSF-1R
Activation loop (A-loop)
Active site
Polypeptide substrate binding site
ATP binding site
CSF-1_receptor
BINDING: ATP.
NP_BIND: ATP.
ACT_SITE: Proton acceptor.
PIRSR
BINDING: ATP
MOD_RES: Phosphotyrosine; by autocatalysis
NP_BIND: ATP.
BINDING: ATP
METAL: Magnesium; via carbonyl oxygen.
ACT_SITE: Proton acceptor.
BINDING: ATP.
NP_BIND: ATP.
METAL: Magnesium.
NP_BIND: ATP.

InterPro GO terms

Panther GO terms
PTHR24416:SF47
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