Q9VC27
Nicastrin
UniProtKB/Swiss-Prot protein
Short name | NICA_DROME |
Length | 695 amino acids |
Species | Drosophila melanogaster (Fruit fly) |
Proteome | UP000000803 |
Gene | Nct |
Function | Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch. It probably represents a stabilizing cofactor required for the assembly of the gamma-secr... |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative domains
phobius: SIGNAL_PEPTIDE_N_REGION
phobius: SIGNAL_PEPTIDE
phobius: SIGNAL_PEPTIDE_H_REGION
phobius: SIGNAL_PEPTIDE_C_REGION
phobius: NON_CYTOPLASMIC_DOMAIN
phobius: TRANSMEMBRANE
phobius: CYTOPLASMIC_DOMAIN
signalp e: SignalP-noTM
tmhmm: TMhelix
InterPro GO terms
biological process
molecular function
- None
cellular component
Panther GO terms
PTHR21092:SF0
biological process
molecular function
- None
cellular component