Q9VC27

Nicastrin

UniProtKB/Swiss-Prot protein
Short nameNICA_DROME
Length695 amino acids
SpeciesDrosophila melanogaster (Fruit fly)
ProteomeUP000000803
GeneNct
Function
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch. It probably represents a stabilizing cofactor required for the assembly of the gamma-secr...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
169550100150200250300350400450500550600650
200400600
Representative families
M28_Nicastrin
DYIGS region

InterPro GO terms

molecular function

  • None

cellular component

Panther GO terms
PTHR21092:SF0
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