Q9ZCI1

tRNA modification GTPase MnmE

UniProtKB/Swiss-Prot protein
Short nameMNME_RICPR
Length445 amino acids
SpeciesRickettsia prowazekii (strain Madrid E)
ProteomeUP000002480
GenemnmE
Function
Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
144550100150200250300350400
200400
trmE
Switch I region
GTP/Mg2+ binding site
G3 box
G2 box
G4 box
G1 box
Switch II region
G5 box
TrmE_N
Homodimer interface
Central domain interface
Tetrahydrofolate-binding site
PIRSR
NP_BIND: GTP.
BINDING: GTP; via amide nitrogen.
NP_BIND: GTP.
METAL: Magnesium.
BINDING: GTP
BINDING: Mg(2+)

InterPro GO terms

Panther GO terms
PTHR42714:SF2
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