A0A023R9I9

Genome polyprotein

UniProtKB/TrEMBL protein
Short nameA0A023R9I9_HE71
Length2193 amino acids
SpeciesHuman enterovirus 71 (EV71)
GeneCN12_49154gpPOL
Function
Acts as a primer for viral RNA replication and remains covalently bound to viral genomic RNA. VPg is uridylylated prior to priming replication into VPg-pUpU. The oriI viral genomic sequence may act as a template for this. The VPg-pUpU is then used as...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
121932004006008001,0001,2001,4001,6001,8002,000
10002000
PCV_3…SF3_…Rhv_5Pic…RhvRhvEnterovirus_RdRp
Representative domains
rhv_likerhv…rhv_like
Drug-binding pocket
Enterovirus_RdRp
Conserved polymerase motif F
Conserved polymerase motif A
RNA binding site
Conserved polymerase motif C
Conserved polymerase motif B
NTP binding site
PIRSR
ACT_SITE: For RdRp activity.
NP_BIND: ATP.
SITE: Cleavage; by protease 3C.

InterPro GO terms

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