A0A1E4SV00

Inosine-5'-monophosphate dehydrogenase

UniProtKB/TrEMBL protein
Short nameA0A1E4SV00_9ASCO
Length522 amino acids
Species[Candida] arabinofermentans NRRL YB-2248
ProteomeUP000094801
GeneCANARDRAFT_238421
Function
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growt...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
152250100150200250300350400450500
200400
IMPDH
Active site
CBS_pair_IMPDH
Ligand binding site I
Ligand binding site II
IMPDH
METAL: Potassium; via carbonyl oxygen.
NP_BIND: NAD.
ACT_SITE: Thioimidate intermediate.
ACT_SITE: Proton acceptor.
PIRSR
ACT_SITE: Thioimidate intermediate.
METAL: Potassium; via carbonyl oxygen.

InterPro GO terms

Panther GO terms
PTHR11911:SF111
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