O80358
Formamidopyrimidine-DNA glycosylase
UniProtKB/Swiss-Prot protein
Short name | FPG_ARATH |
Length | 390 amino acids |
Species | Arabidopsis thaliana (Mouse-ear cress) |
Proteome | UP000006548 |
Gene | FPG1 |
Function | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as a DNA glycosylase that recognizes and removes damaged bases. Can process efficiently 4,6-diamino-5-formamidopyrimidine (FapyA), 2,6-diamino-4- hydroxy-5-form... |
Family membership | |
Isoforms |
Entry matches to this protein
Representative families
Representative domains
InterPro GO terms
biological process
molecular function
- DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0003906)
- zinc ion binding (GO:0008270)
- DNA N-glycosylase activity (GO:0019104)
- damaged DNA binding (GO:0003684)
- hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799)
- oxidized purine nucleobase lesion DNA N-glycosylase activity (GO:0008534)
- nucleic acid binding (GO:0003676)
cellular component
- None