P05024
Sodium/potassium-transporting ATPase subunit alpha-1
UniProtKB/Swiss-Prot protein
Short name | AT1A1_PIG |
Length | 1021 amino acids |
Species | Sus scrofa (Pig) |
Proteome | UP000008227 |
Gene | ATP1A1 |
Function | This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium io... |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative families
Representative domains
K binding site
Na binding site
Phosphorylation site
ATP-binding site
Alpha-subunit/beta-subunit interface
Probable role in phosphate transfer from ATP
Coordinates with phosphate oxygen from ATP
Mg2+ ligand
Nucleophile: attacks gamma phosphate moiety of ATP to form covalent intermediate, Mg2+ ligand
Conserved in all p-type atpases
Stabilizes transition state of phosphoryl transfer by contacting beta & gamma phosphate oxygens of ATP
coils: Coil
phobius: CYTOPLASMIC_DOMAIN
phobius: TRANSMEMBRANE
phobius: NON_CYTOPLASMIC_DOMAIN
tmhmm: TMhelix
InterPro GO terms
Panther GO terms
PTHR43294:SF9
biological process
molecular function