P41743
Protein kinase C iota type
UniProtKB/Swiss-Prot protein
Short name | KPCI_HUMAN |
Length | 596 amino acids |
Species | Homo sapiens (Human) |
Proteome | UP000005640 |
Gene | PRKCI |
Function | Calcium- and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulat... |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative families
Representative domains
Polypeptide substrate binding site
Turn motif phosphorylation site
Activation loop (A-loop)
ATP binding site
Hydrophobic motif (HM)
Active site
PB1 interaction surface
ACT_SITE: Proton acceptor.
NP_BIND: ATP.
BINDING: ATP.
PIRSR
BINDING: ATP
NP_BIND: ATP.
BINDING: ATP.
BINDING: ATP.
METAL: Magnesium; via carbonyl oxygen.
BINDING: ATP; via carbonyl oxygen.
METAL: Magnesium.
CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
ACT_SITE: Proton acceptor.
NP_BIND: ATP.
BINDING: ATP.
InterPro GO terms
biological process
molecular function
cellular component
- None