P52757

Beta-chimaerin

UniProtKB/Swiss-Prot protein
Short nameCHIO_HUMAN
Length468 amino acids
SpeciesHomo sapiens (Human)
ProteomeUP000005640
GeneCHN2
Function
GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors
Family membership
Isoforms
Entry matches to this protein
Feature Display Mode
Summary
Full
146850100150200250300350400450
200400
RhoGAP_chimaerin
Putative GTPase interaction site
Catalytic residue
SH2_a2chimerin_b2…
Phosphotyrosine binding pocket
Hydrophobic binding pocket
C1_betaCHN
Putative DAG/PE binding site

InterPro GO terms

Panther GO terms
PTHR46075:SF4

cellular component

  • None
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