P63092
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
UniProtKB/Swiss-Prot protein
Short name | GNAS2_HUMAN |
Length | 394 amino acids |
Species | Homo sapiens (Human) |
Proteome | UP000005640 |
Gene | GNAS |
Function | Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:12391161, PubMed:17110384, PubMed:21488135, PubMed:26206488, PubMed:8702665, PubMed:1020... |
Family membership | |
Isoforms |
Entry matches to this protein
Representative families
Representative domains
GoLoco binding site
GTP/Mg2+ binding site
Putative receptor binding site
G2 box
Switch I region
G4 box
Beta - gamma complex interaction site
Switch II region
Adenylyl cyclase interaction site
G5 box
G1 box
G3 box
PIRSR
BINDING: Mg(2+)
coils: Coil
InterPro GO terms
Panther GO terms
PTHR10218:SF357
biological process
molecular function
- G protein-coupled receptor binding (GO:0001664)
- GTPase activity (GO:0003924)
- insulin-like growth factor receptor binding (GO:0005159)
- G-protein beta/gamma-subunit complex binding (GO:0031683)
- beta-2 adrenergic receptor binding (GO:0031698)
- D1 dopamine receptor binding (GO:0031748)
- mu-type opioid receptor binding (GO:0031852)
- ionotropic glutamate receptor binding (GO:0035255)
- corticotropin-releasing hormone receptor 1 binding (GO:0051430)
cellular component