Q1IGF3
Formamidopyrimidine-DNA glycosylase
UniProtKB/Swiss-Prot protein
Short name | FPG_PSEE4 |
Length | 270 amino acids |
Species | Pseudomonas entomophila (strain L48) |
Gene | mutM |
Function | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as a DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurin... |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative families
Representative domains
Putative reading head residues
8OG recognition residue
Intercalation triad
DNA binding site
Catalytic residue
H2TH interface
Putative catalytic residues
Turnover-facilitating residue
InterPro GO terms
biological process
molecular function
- DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0003906)
- zinc ion binding (GO:0008270)
- DNA N-glycosylase activity (GO:0019104)
- damaged DNA binding (GO:0003684)
- hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799)
- oxidized purine nucleobase lesion DNA N-glycosylase activity (GO:0008534)
- nucleic acid binding (GO:0003676)
- DNA binding (GO:0003677)
cellular component
- None