Q6SZW1

NAD(+) hydrolase SARM1

UniProtKB/Swiss-Prot protein
Short nameSARM1_HUMAN
Length724 amino acids
SpeciesHomo sapiens (Human)
ProteomeUP000005640
GeneSARM1
Function
NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (PubMed:25908823, PubMed:27671644, PubMed:28334607). Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signali...
Family membership
Isoforms
Entry matches to this protein
Feature Display Mode
Summary
Full
1724100200300400500600700
200400600

InterPro GO terms

Panther GO terms
PTHR22998:SF1

molecular function

  • None

cellular component

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