Q6SZW1
NAD(+) hydrolase SARM1
UniProtKB/Swiss-Prot protein
Short name | SARM1_HUMAN |
Length | 724 amino acids |
Species | Homo sapiens (Human) |
Proteome | UP000005640 |
Gene | SARM1 |
Function | NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (PubMed:25908823, PubMed:27671644, PubMed:28334607). Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signali... |
Family membership | |
Isoforms |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative domains
coils: Coil
phobius: SIGNAL_PEPTIDE_N_REGION
phobius: SIGNAL_PEPTIDE
phobius: SIGNAL_PEPTIDE_H_REGION
phobius: SIGNAL_PEPTIDE_C_REGION
phobius: NON_CYTOPLASMIC_DOMAIN
signalp e: SignalP-noTM
InterPro GO terms
biological process
molecular function
cellular component
- None
Panther GO terms
PTHR22998:SF1
biological process
molecular function
- None
cellular component