A5U706
3-isopropylmalate dehydrogenase
UniProtKB/Swiss-Prot protein
Short name | LEU3_MYCTA |
Length | 336 amino acids |
Species | Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) |
Proteome | UP000001988 |
Gene | leuB |
Function | Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate |
Family membership |
Entry matches to this protein
Representative families
Representative domains
PIRSR
BINDING: substrate
BINDING: Mg(2+)
SITE: Critical for catalysis
InterPro GO terms
biological process
molecular function
cellular component
- None