Q07496

Ephrin type-A receptor 4

UniProtKB/Swiss-Prot protein
Short nameEPHA4_CHICK
Length986 amino acids
SpeciesGallus gallus (Chicken)
ProteomeUP000000539
GeneEPHA4
Function
Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forw...
Family membership
Entry matches to this protein
Feature Display Mode
Summary
Full
1986100200300400500600700800900
500
E…EPH_LBDFN3FN3EphA…SAM_E…PTKc_EphR_A
Representative domains
FN3FN3
Interdomain contacts
Cytokine receptor motif
PTKc_EphR_A
Activation loop (A-loop)
Active site
ATP binding site
Polypeptide substrate binding site
SAM_E…
Putative phosphorylation site
Homodimer interface
EphR_LBD_A4
Ephrin binding site
TyrPK_ephrin_receptor
BINDING: ATP
ACT_SITE: Proton acceptor
DISULFID:
PIRSR
ACT_SITE: Proton acceptor
BINDING: ATP
NP_BIND: ATP.
BINDING: ATP.
NP_BIND: ATP.
METAL: Magnesium; via carbonyl oxygen.
METAL: Magnesium.
NP_BIND: ATP.

InterPro GO terms

Panther GO terms
PTHR46877:SF18
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.