A0A011PFG4
Methionine synthase
UniProtKB/TrEMBL protein
Short name | A0A011PFG4_9PROT |
Length | 1235 amino acids |
Species | Candidatus Accumulibacter sp. SK-11 |
Proteome | UP000020226 |
Gene | metH |
Function | Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate |
Family membership |
Entry matches to this protein
Feature Display Mode
Summary
Full
Representative families
Representative domains
Substrate binding pocket
B12 binding site
Cobalt ligand
BINDING: Methylcob(III)alamin.
REGION: Methylcob(III)alamin binding.
BINDING: Methylcob(III)alamin; via amide nitrogen.
REGION: S-adenosyl-L-methionine binding.
BINDING: S-adenosyl-L-methionine.
BINDING: S-adenosyl-L-methionine; via carbonyl oxygen.
BINDING: methylcob(III)alamin / Co; axial binding residue.
BINDING: Zn(2+).
PIRSR
METAL: Zinc.
InterPro GO terms
Panther GO terms
PTHR45833:SF1
biological process
molecular function
cellular component