A0A0D9RSN4
N-lysine methyltransferase SMYD2
UniProtKB/TrEMBL protein
Short name | A0A0D9RSN4_CHLSB |
Length | 433 amino acids |
Species | Chlorocebus sabaeus (Green monkey) |
Proteome | UP000029965 |
Gene | SMYD2 |
Function | Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even high... |
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Summary
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Representative families
Representative domains
Inhibitor binding site
Zn binding site
Active site
Putative polypeptide substrate binding site
SAM binding site
coils: Coil
InterPro GO terms
biological process
- None
molecular function
cellular component
- None
Panther GO terms
PTHR12197:SF193
biological process
molecular function
cellular component