A0A8C7C1V0
Peroxisome proliferator-activated receptor gamma
UniProtKB/TrEMBL protein
Short name | A0A8C7C1V0_ONCKI |
Length | 508 amino acids |
Species | Oncorhynchus kisutch (Coho salmon) |
Proteome | UP000694557 |
Gene | PPARG |
Function | Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes... |
Family membership |
Entry matches to this protein
Representative families
Representative domains
Coactivator recognition site
Heterodimer interface
Ligand binding site
Dimer interface
DNA binding site
Zinc binding site
PIRSR
BINDING: Phosphatidylglycerol phosphate.
InterPro GO terms
biological process
molecular function
cellular component
Panther GO terms
PTHR24082:SF488
biological process
- negative regulation of transcription by RNA polymerase II (GO:0000122)
- fatty acid metabolic process (GO:0006631)
- hormone-mediated signaling pathway (GO:0009755)
- negative regulation of cholesterol storage (GO:0010887)
- regulation of lipid metabolic process (GO:0019216)
- cell differentiation (GO:0030154)
- positive regulation of fatty acid metabolic process (GO:0045923)
- positive regulation of transcription by RNA polymerase II (GO:0045944)
- negative regulation of inflammatory response (GO:0050728)
molecular function
cellular component
- None