H2R842

N-lysine methyltransferase SMYD2

UniProtKB/TrEMBL protein
Short nameH2R842_PANTR
Length433 amino acids
SpeciesPan troglodytes (Chimpanzee)
ProteomeUP000002277
GeneSMYD2
Function
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even high...
Family membership
Entry matches to this protein

InterPro GO terms

Panther GO terms
PTHR12197:SF193
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