UP000000276

Corynebacterium pseudotuberculosis (strain C231)

UniProtKB proteome
Proteome ID
UP000000276
StrainC231
TaxonomyCorynebacterium pseudotuberculosis (strain C231)

Description

Bacteria from the genus Corynebacterium are Gram-positive, nonmotile rods which include both pathogenic and non-pathogenic species that can live in a large variety of habitats. In addition to being animal and human pathogens, they have been isolated from soil, plant material, waste water, and dairy products. Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that causes caseous lymphadenitis (CLA, also known as cheesy gland) disease in sheep, goats and other small ruminants worldwide. CLA causes reduction of wool, meat and milk yields, decreased fertility, increased culling and condemnation of skins and carcasses in slaughter houses. Once established in a herd or flock, CLA eradication is problematic due to the inefficacy of antimicrobial therapy. C.pseudotuberculosis exhibits pleomorphic forms, such as coccoids and filamentous rods, ranging in size from 0.5 um to 0.6 um by 1.0 um to 3.0 um. It is a non-sporulating, non-capsulated and non-motile bacterium; however, it has fimbriae. This bacterium is a facultative anaerobe and grows best at 37 degrees Celsius, at a pH of 7.0 to 7.2. It was first isolated in 1888 and fully described in 1894. It is able to survive in the environment for a few weeks, which helps it spread within herds and flocks, infection seems to occur through contamination of wounds. It very occasionally infects humans. Strain C231, also known as CpC231, was isolated from sheep in Australia (adapted from PMID 16472520).

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