Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Proteome ID | UP000000314 |
Strain | GS115 |
Taxonomy | Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris) |
Description
Pichia pastoris has been reassigned to the genus Komagataella after phylogenetic analysis of gene sequences, and split into three species, K. pastoris, K. phaffii, and K. pseudopastoris. These species are facultative methylotrophic yeasts: they are able to use single carbon compounds (e.g. methanol or methane) or multi-carbon compounds with no carbon-carbon bonds (e.g. dimethyl ether or dimethylamine) as a food source. Pichia pastoris has been used extensively as an expression system for protein production because of its high growth rate, low cost of culture, and because it is able to produce proteins with disulfide bonds and glycosylation. The genome sequence was published in 2009 for Komagataella pastoris strain GS115. It consists of 9.4Mb in 4 chromosomes with 5,313 predicted protein-coding genes.