UP000000377

Streptomyces bingchenggensis (strain BCW-1)

UniProtKB proteome
Proteome ID
UP000000377
StrainBCW-1
TaxonomyStreptomyces bingchenggensis (strain BCW-1)

Description

The genus Streptomyces consists of soil and water Gram positive filamentous bacteria well known for their ability to produce complex secondary metabolites including many antibiotics. Additionally they undergo complex multicellular development, with spores germinating to form a branched, multinucleoid substrate mycelium, which then produces an aerial mycelium which septates into uninucleoid spores. Streptomyces is also unusual in having linear chromosomes with terminal inverted repeats with terminal proteins covalently bound to their 5' ends. Streptomyces bingchenggensis (China General Microbiology Culture Collection Center CGMCC1734) is a soil bacterium isolated in Harbin, China. It is probably the largest bacterial genome that has been sequenced to date (August 2010) at almost 12 Mb. It produces milbemycins (commercially important anthelmintic macrolide compounds), other insecticidal antibiotics and at least a few cyclic pentapeptides and is thus interesting for its secondary metabolite producing capabilities (adapted from PMID 20581206).

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