CL0029

Cupin

Pfam clan
Accession
CL0029
Member databasePfam
AuthorsBateman A

Description

This clan represents the conserved barrel domain of the 'cupin' superfamily [1] ('cupa' is the Latin term for a small barrel). The cupin fold is found in a wide variety of enzymes, but notably contains the non-enzymatic seed storage proteins also.

References

1. Cupins: a new superfamily of functionally diverse proteins that include germins and plant storage proteins. Dunwell JM Biotechnol Genet Eng Rev 15, 1-32, (1998). PMID: 9573603

7.1e-61.9e-34.5e-32e-52.6e-111.5e-41.3e-81.6e-36.2e-53.7e-31.7e-62.4e-39.5e-57.7e-153.6e-54.9e-51.2e-35.3e-32.4e-48.3e-44e-32.2e-46.3e-32.9e-31.9e-55.5e-59.5e-42.8e-84.8e-66.8e-78.4e-92.1e-118.6e-59.1e-38.3e-61.1e-31.4e-51.9e-61.3e-72.6e-145.8e-35e-75.4e-111.9e-43e-67.9e-83.9e-69e-148.8e-56.6e-183.4e-155.5e-43.1e-44e-33.5e-55.2e-31.8e-61e-31.3e-157.5e-51.3e-211.6e-65.8e-82.1e-49.7e-55.6e-45.2e-32.9e-71.9e-72.8e-103.9e-53.6e-101.3e-75.5e-32.2e-31.6e-33.7e-33.6e-41.4e-38e-36.5e-31.5e-31e-27.4e-99.8e-3PMI_typeI_C - Phosphomannose isomerase type I C-terminalPirin_C - Pirin C-terminal cupin domainAuxin_BP - Auxin binding proteinJmjN - jmjN domainLyx_isomer - D-lyxose isomeraseHutD - HutDCupin_5 - Cupin superfamily (DUF985)Ectoine_synth - Ectoine synthaseCDO_I - Cysteine dioxygenase type IGPI - Glucose-6-phosphate isomerase (GPI)PCO_ADO - PCO_ADOCupin_2 - Cupin domainJmjC_2 - JmjC domainToxT_N - ToxT, N-terminal cupin-like domainWelO5 - Carrier-protein-independent halogenase WelO52OG-FeII_Oxy - 2OG-Fe(II) oxygenase superfamilyAraC_binding - AraC-like ligand binding domainAraC_N - AraC-type transcriptional regulator N-terminusARD - ARD/ARD' familyCupin_1 - CupinDUF386 - YhcH/YjgK/YiaLHgmA_C - Homogentisate 1,2-dioxygenase C-terminalDUF1971 - Domain of unknown function (DUF1971)Asp_Arg_Hydrox - Aspartyl/Asparaginyl beta-hydroxylaseCsiD - CsiDAIM24 - Mitochondrial biogenesis AIM24FdtA - WxcM-like, C-terminalPpnp - Pyrimidine/purine nucleoside phosphorylaseJmjC - JmjC domain, hydroxylasedTDP_sugar_isom - dTDP-4-dehydrorhamnose 3,5-epimerasePopeye - Popeye protein conserved regionERG2_Sigma1R - ERG2 and Sigma1 receptor like proteinMannoseP_isomer - Mannose-6-phosphate isomerase C-terminalEutQ - Ethanolamine utilisation protein EutQKduI - KduI/IolB familyTauD - Taurine catabolism dioxygenase TauD, TfdA familyVIT - Vault protein inter-alpha-trypsin domainPhyH - Phytanoyl-CoA dioxygenase (PhyH)Ureidogly_lyase - Ureidoglycolate lyase2OG-Fe_Oxy_2 - 2OG-Fe dioxygenasePirin - PirinOfd1_CTDD - Oxoglutarate and iron-dependent oxygenase degradation C-term3-HAO - 3-hydroxyanthranilic acid dioxygenaseOxygenase-NA - Oxygenase, catalysing oxidative methylation of damaged DNACENP-C_C - Mif2/CENP-C like2OG-FeII_Oxy_2 - 2OG-Fe(II) oxygenase superfamily2OG-FeII_Oxy_4 - 2OG-Fe(II) oxygenase superfamily2OG-FeII_Oxy_5 - Putative 2OG-Fe(II) oxygenaseDIOX_N - non-haem dioxygenase in morphine synthesis N-terminal2OG-FeII_Oxy_3 - 2OG-Fe(II) oxygenase superfamilyCupin_8 - Cupin-like domainVIT_2 - Vault protein inter-alpha-trypsin domainDUF4246 - Protein of unknown function (DUF4246)Kdo_hydroxy - 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylaseDMSP_lyase - Dimethlysulfonioproprionate lyaseDUF5070 - Domain of unknown function (DUF5070)DUF4867 - Domain of unknown function (DUF4867)AraC_binding_2 - AraC-binding-like domainDUF4437 - Domain of unknown function (DUF4437)Cupin_3 - EutQ-like cupin domaincNMP_binding - Cyclic nucleotide-binding domainPirin_C_2 - Quercetinase C-terminal cupin domainAUDH_Cupin - Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domainDUF6016 - Domain of unknown function (DUF6016)HgmA_N - Homogentisate 1,2-dioxygenase N-terminalPMI_typeI_cat - Phosphomannose isomerase type I, catalytic domain2OG-FeII_Oxy_6 - Tet-like 2OG-Fe(II) oxygenase superfamilyPox_C4_C10 - Poxvirus C4/C10 proteinMPI_cupin_dom - Mannose-6-phosphate isomerase, cupin domainFTO_NTD - FTO catalytic domainGig2-like - Gig2-likeTet_JBP - Oxygenase domain of the 2OGFeDO superfamilyCupin_6 - CupinCupin_7 - ChrR Cupin-like domainExsA_N - ExsA N-terminal regulatory domain
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