1adz

THE SOLUTION STRUCTURE OF THE SECOND KUNITZ DOMAIN OF TISSUE FACTOR PATHWAY INHIBITOR, NMR, 30 STRUCTURES

PDB structure
Accession
1adz
Experiment typeNMR
ChainsA
Released25 February 1998

References

1. The second Kunitz domain of human tissue factor pathway inhibitor: cloning, structure determination and interaction with factor Xa. Burgering, M.J., Orbons, L.P., van der Doelen, A., Mulders, J., Theunissen, H.J., Grootenhuis, P.D., Bode, W., Huber, R., Stubbs, M.T. J. Mol. Biol. 269, 395-407, (1997). View articlePMID: 9199408

2. Structural Aspects of Factor Xa Inhibition Stubbs II, M.T. Curr. Pharm. Des. 2, 543, (1996).

3. X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition. Brandstetter, H., Kuhne, A., Bode, W., Huber, R., von der Saal, W., Wirthensohn, K., Engh, R.A. J Biol Chem 271, 29988, (1996). View articlePMID: 8939944

4. The Ornithodorin-Thrombin Crystal Structure, a Key to the Tap Enigma? Van De Locht, A., Stubbs, M.T., Bode, W., Friedrich, T., Bollschweiler, C., Hoffken, W., Huber, R. EMBO J. 15, 6011, (1996).

5. Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin. Stubbs, M.T., Huber, R., Bode, W. FEBS Lett 375, 103, (1995). View articlePMID: 7498454

6. Structure of human des(1-45) factor Xa at 2.2 A resolution. Padmanabhan, K., Padmanabhan, K.P., Tulinsky, A., Park, C.H., Bode, W., Huber, R., Blankenship, D.T., Cardin, A.D., Kisiel, W. J Mol Biol 232, 947, (1993). View articlePMID: 8355279

7. Determination of a high-quality nuclear magnetic resonance solution structure of the bovine pancreatic trypsin inhibitor and comparison with three crystal structures. Berndt, K.D., Guntert, P., Orbons, L.P., Wuthrich, K. J Mol Biol 227, 757, (1992). View articlePMID: 1383552

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