1jkx

Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase

PDB structure
Accession
1jkx
Experiment typeX-ray
Resolution1.6 Å
ChainsA, B, C, D
Released30 November 2001

References

1. Unexpected formation of an epoxide-derived multisubstrate adduct inhibitor on the active site of GAR transformylase. Greasley, S.E., Marsilje, T.H., Cai, H., Baker, S., Benkovic, S.J., Boger, D.L., Wilson, I.A. Biochemistry 40, 13538-13547, (2001). View articlePMID: 11695901

2. Functionalized analogues of 5,8,10-trideazafolate: Development of an enzyme-assembled tight binding inhibitor of GAR Tfase and a potential irreversible inhibitor of AICAR Tfase Boger, D.L., Haynes, N.-E., Warren, M.S., Ramcharan, J., Kitos, P.A., Benkovic, S.J. Bioorg. Med. Chem. 5, 1839-1846, (1997). View article

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