2p2i
Crystal structure of the VEGFR2 kinase domain in complex with a nicotinamide inhibitor
PDB structure
Accession | 2p2i |
Experiment type | X-ray |
Resolution | 2.4 Å |
Chains | A, B |
Released | 20 March 2007 |
References
1. Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor Hodous, B.L., Geuns-Meyer, S.D., Hughes, P.E., Albrecht, B.K., Bellon, S., Bready, J., Caenepeel, S., Cee, V.J., Chaffee, S.C., Coxon, A., Emery, M., Fretland, J., Gallant, P., Gu, Y., Hoffman, D., Johnson, R.E., Kendall, R., Kim, J.L., Long, A.M., Morrison, M., Olivieri, P.R., Patel, V.F., Polverino, A., Rose, P., Tempest, P., Wang, L., Whittington, D.A., Zhao, H. J. Med. Chem. 50, 611-626, (2007). View articlePMID: 17253678