6ak2

Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018

PDB structure
Accession
6ak2
Experiment typeX-ray
Resolution1.868 Å
ChainsA, B, D, E
Released4 September 2019

Chain A ( Q9JI92)

Domains in the chain
1811020304050607080
20406080GIREVILCKDQDGKIGLRLKSVDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIR
PDB: Chain A

Chain B ( Q9JI92)

Domains in the chain
1811020304050607080
20406080GIREVILCKDQDGKIGLRLKSVDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIR
PDB: Chain B

References

1. A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma. Haugaard-Kedstrom, L.M., Clemmensen, L.S., Sereikaite, V., Jin, Z., Fernandes, E.F.A., Wind, B., Abalde-Gil, F., Daberger, J., Vistrup-Parry, M., Aguilar-Morante, D., Leblanc, R., Egea-Jimenez, A.L., Albrigtsen, M., Jensen, K.E., Jensen, T.M.T., Ivarsson, Y., Vincentelli, R., Hamerlik, P., Andersen, J.H., Zimmermann, P., Lee, W., Stromgaard, K. J. Med. Chem. 64, 1423-1434, (2021). View articlePMID: 33502198

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