8d0f

Human SARM1 TIR domain bound to NB-2-ADPR

PDB structure
Accession
8d0f
Experiment typeX-ray
Resolution1.74 Å
ChainsA, B
Released21 September 2022

References

1. Uncompetitive, adduct-forming SARM1 inhibitors are neuroprotective in preclinical models of nerve injury and disease. Bratkowski, M., Burdett, T.C., Danao, J., Wang, X., Mathur, P., Gu, W., Beckstead, J.A., Talreja, S., Yang, Y.S., Danko, G., Park, J.H., Walton, M., Brown, S.P., Tegley, C.M., Joseph, P.R.B., Reynolds, C.H., Sambashivan, S. Neuron 110, 3711, (2022). View articlePMID: 36087583

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