8f0k

Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385

PDB structure
Accession
8f0k
Experiment typeCryo-EM
Resolution1.9 Å
ChainsA, B, E, G, N, P, R
Released2 August 2023

Chain A ( P63092)

Domains in the chain

Chain E ( O60896)

Domains in the chain
114920406080100120140
50100150
PDB: Chain E

Chain G ( P59768)

Domains in the chain

Chain N

Domains in the chain

Chain P ( P10997)

Domains in the chain
1385101520253035
102030KCNTATCATQRLANFLVHKSNNFGPILPPTNVGSNTYX
PDB: Chain P
CALCITONIN
Representative domains
Calcitonin_peptide-likeCALCITONIN

Chain R ( P30988)

Domains in the chain
150150100150200250300350400450500
200400
PDB: Chain R

References

1. Structural insight into selectivity of amylin and calcitonin receptor agonists. Cao, J., Belousoff, M.J., Gerrard, E., Danev, R., Fletcher, M.M., Dal Maso, E., Schreuder, H., Lorenz, K., Evers, A., Tiwari, G., Besenius, M., Li, Z., Johnson, R.M., Wootten, D., Sexton, P.M. Nat. Chem. Biol. 20, 162-169, (2024). View articlePMID: 37537379

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.