$VAR1 = undef;
Summary for peptidase M14.003: carboxypeptidase B
| Names | |
|---|---|
| MEROPS Name | carboxypeptidase B |
| Other names | carboxypeptidase B1, CPB1 g.p. (Homo sapiens), pancreatic carboxypeptidase B, protaminase, tissue carboxypeptidase B |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan MC >> Subclan (none) >> Family M14 >> Subfamily A >> M14.003 |
| Holotype | carboxypeptidase B (Bos taurus), Uniprot accession P00732 (peptidase unit: 1-306), MERNUM MER0001196 |
| History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
| Activity | |||
|---|---|---|---|
| Catalytic type | Metallo | ||
| Peplist | Included in the Peplist with identifier PL00208 | ||
| NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.17 (Metallocarboxypeptidases) >> Peptidase 3.4.17.2 | ||
| Enzymology | BRENDA database | ||
| Activity status | human: active (Aviles & Vendrell, 2004) mouse: active (by similarity) | ||
| Physiology | Role in mammalian alimentary digestion. | ||
| Pathways | KEGG | Pancreatic secretion | |
| KEGG | Protein digestion and absorption | ||
| Other databases | TREEFAM | http://www.treefam.org/family/TF317197 | |
| Human genetics | ||||||
|---|---|---|---|---|---|---|
| Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
| CPB1 | 3q24 | ENSG00000153002 | 1360 | CPB1 | 114852 | |
| Mouse genetics | ||||||
| Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
| Cpb1 | 3:A2 | ENSMUSG00000011463 | 76703 | MGI:1923953 | ||
