MetaboLights
An octadecenoic acid with a double bond at C-9.
Identification
octadec-9-enoic acid
18:1, n-9
9-octadecenoic acid
C18:1, n-9
Delta(9)-octadecenoic acid
Species
homo sapiens
NCBI:txid9606 25502724
Europe PubMed Central results
Improving Adherence to Smoking Cessation Treatment: Smoking Outcomes in a Web-based Randomized Trial.
Author: Graham AL, Papandonatos GD, Cha S, Erar B, Amato MS.
Abstract: <h4>Background</h4>Partial adherence in Internet smoking cessation interventions presents treatment and evaluation challenges. Increasing adherence may improve outcomes.<h4>Purpose</h4>To present smoking outcomes from an Internet randomized trial of two strategies to encourage adherence to tobacco dependence treatment components: (i) a social network (SN) strategy to integrate smokers into an online community and (ii) free nicotine replacement therapy (NRT). In addition to intent-to-treat analyses, we used novel statistical methods to distinguish the impact of treatment assignment from treatment utilization.<h4>Methods</h4>A total of 5,290 current smokers on a cessation website (WEB) were randomized to WEB, WEB + SN, WEB + NRT, or WEB + SN + NRT. The main outcome was 30-day point prevalence abstinence at 3 and 9 months post-randomization. Adherence measures included self-reported medication use (meds), and website metrics of skills training (sk) and community use (comm). Inverse Probability of Retention Weighting and Inverse Probability of Treatment Weighting jointly addressed dropout and treatment selection. Propensity weights were used to calculate Average Treatment effects on the Treated.<h4>Results</h4>Treatment assignment analyses showed no effects on abstinence for either adherence strategy. Abstinence rates were 25.7%-32.2% among participants that used all three treatment components (sk+comm +meds).Treatment utilization analyses revealed that among such participants, sk+comm+meds yielded large percentage point increases in 3-month abstinence rates over sk alone across arms: WEB = 20.6 (95% CI = 10.8, 30.4), WEB + SN = 19.2 (95% CI = 11.1, 27.3), WEB + NRT = 13.1 (95% CI = 4.1, 22.0), and WEB + SN + NRT = 20.0 (95% CI = 12.2, 27.7).<h4>Conclusions</h4>Novel propensity weighting approaches can serve as a model for establishing efficacy of Internet interventions and yield important insights about mechanisms.<h4>Clinical trials.gov</h4>NCT01544153.
DOI: 10.1093/abm/kax023
Essential oil composition of Prasium majus from Croatia.
Author: Jerković I, Suste M, Males Z, Pilepić KH.
Abstract: The essential oils from the aerial parts of Prasium majus L., collected during two years in Croatia, were analysed by GC and GC/MS. Fifty-two compounds were identified, representing 90.3-91.8% of the total oils. The major constituents in both samples were fatty acids (particularly hexadecanoic acid and (Z)-octadec-9-enoic acid), lower aliphatic alcohols, aldehydes and acids (major ones oct-1-en-3-ol and (E,E)-hepta-2,4-dienal) and phenylpropane derivatives (e.g. eugenol). Beta-Caryophyllene was the most abundant terpene and (E)-beta-ionone was the major norisoprenoid.
Capillary electrophoresis with capacitively coupled contactless conductivity detection for the determination of cis/trans isomers of octadec-9-enoic acid and other long chain fatty acids.
Author: Wong YF, Saad B, Makahleh A.
Abstract: A capillary electrophoresis (CE)-capacitively coupled contactless conductivity detection (C(4)D) method for the simultaneous separation of eleven underivatized fatty acids (FAs), namely, lauric, myristic, tridecanoic (internal standard), pentadecanoic, palmitic, stearic, oleic, elaidic, linoleic, linolenic and arachidic acids is described. The separation was carried out in normal polarity mode at 20 °C, 30 kV and using hydrodynamic injection (50 mbar for 1 s). The separation was achieved in a bare fused-silica capillary (70 cm × 75 μm i.d.) using a background electrolyte of methyl-β-cyclodextrin (~6 mM) and heptakis-(2,3,6-tri-O-methyl)-β-cyclodextrin (~8 mM) dissolved in a mixture of Na2HPO4/KH2PO4 (5 mM, pH 7.4):ACN:MeOH:n-octanol (3:4:2.5:0.5, v/v/v/v). C(4)D parameters were set at fixed amplitude of 100 V and frequency of 1000 kHz. The developed method was validated. Calibration curves of the ten FAs were well correlated (r(2)>0.99) within the range of 5-250 μg mL(-1) for lauric acid, and 3-250 μg mL(-1) for the other FAs. The method was simple and sensitive with detection limits (S/N=3) of 0.9-1.9 μg mL(-1) and good relative standard deviations of intra- and inter-day for migration times and peak areas (≤9.7%) were achieved. The method was applied to the determination of FAs in margarine samples. The proposed method offers distinct advantages over the GC and HPLC methods, especially in terms of simplicity (without derivatization) and sensitivity.
Acinetobacter harbinensis sp. nov., isolated from river water.
Author: Li W, Zhang D, Huang X, Qin W.
Abstract: A bacterial strain, HITLi 7T, with nitrifying ability was isolated from the surface water of the Songhua River in China. Cells were Gram-stain-negative, strictly aerobic, oxidase-negative, non-motile coccobacilli, capable of growth in mineral media with acetate as the sole carbon source and ammonia as the sole source of nitrogen. The cells did not grow at 37 °C, but did grow at 2 °C. The DNA G+C content was 45.5 mol%. Results of 16S rRNA gene sequence analysis indicated a close relationship between this isolate and Acinetobacter lwoffii (98.4% similarity for strain DSM 2403T). rpoB and gyrB gene sequences did not show significant similarity with those from other species of the genus Acinetobacter. Predominant cellular fatty acids were 9-octadecenoic acid (C18 : 1ω9c) and summed feature 4 (iso-C15:0 2-OH and/or C16:1ω7c). Acid was not produced from d-glucose, and gelatin was not hydrolysed by the isolate. Genotypic, phenotypic and chemotaxonomic data from this study indicate that the isolate should be classified as a representative of a novel species of the genus Acinetobacter. The name Acinetobacter harbinensis sp. nov. is proposed for the novel species, with HITLi 7T (=CGMCC 1.12528T=KCTC 32411T) as the type strain.