A natural product found in Talaromyces thermophilus.

Identification

Molecular Formula
C13H13N3O2
Mass
243.26120
Monoisotopic Mass
243.10078
Charge
0
InChI
InChI=1S/C13H13N3O2/c17-12-7-15-13(18)11(16-12)5-8-6-14-10-4-2-1-3-9(8)10/h1-4,6,11,14H,5,7H2,(H,15,18)(H,16,17)/t11-/m0/s1
InChIKey
IFQZEERDQXQTLJ-NSHDSACASA-N
SMILES
O=C1CNC(=O)[C@H](Cc2c[nH]c3ccccc23)N1
Synonyms

(3S)-3-(1H-indol-3-ylmethyl)piperazine-2,5-dione

Species

talaromyces thermophilus

NCBI:txid2856521967034

Europe PubMed Central results


Isolation of talathermophilins from the thermophilic fungus Talaromyces thermophilus YM3-4.

Author: Guo JP, Tan JL, Wang YL, Wu HY, Zhang CP, Niu XM, Pan WZ, Huang XW, Zhang KQ.

Abstract: Six indole alkaloids with various levels of prenylation were isolated from the thermophilic fungus Talaromyces thermophilus strain YM3-4. Their structures were identified by NMR and MS spectroscopic analyses. Compounds 1 and 2 are new analogues of the key versatile precursor notoamide E. Compound 3 is a novel analogue of preechinulin, and compound 4 was reported as a natural occurring cyclo(glycyltryptophyl) for the first time. The metabolite profile of this thermophilic organism displayed a biosynthetic pathway for talathermophilins.